EFFECT OF METHOTREXATE THERAPY ON VISUAL FUNCTIONS

Aim: To find the effect of Methotrexate therapy on visual functions (visual acuity, contrast sensitivity, color vision, glare field) and ocular adnexa
 Study Design: Descriptive cross-sectional study
 Place Duration: College Ophthalmology Allied Vision Sciences (COAVS), Mayo Hospital Lahore from September 2016 to November 2016.
 Material Methods: A total 30 patients having psoriasis rheumatoid arthritis taking methotrexate with different doses durations were questioned through a specified performa then examined for changes in adnexa functions. Results saved Excel Sheets analyzed SPSS v.25.0.
 Results: Patients found have affected vision field being more as compared other Dosage significantly affects (p=.002) (p=.001). While terms duration, it was that there is significant relation (p=.006) between duration same (p=.001).
 Conclusion: has less sensitivity adnexa. However, due therapy, neurological defects occur long term (1-2 years) therapy.